Publications and patents 2014 - Archive

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  1. Aburizaiza AS, Mattes FM, Azhar EI, Hassan AM, Memish ZA, Muth D, Meyer B, Lattwein E, Müller MA, Drosten C. Investigation of anti-Middle East respiratory syndrome antibodies in blood donors and slaughterhouse workers in Jeddah and Makkah, Saudi Arabia, fall 2012. J Infect Dis 209(2): 243–246 (2014).
  2. Balint B, Jarius S, Nagel S, Haberkorn U, Probst C, Blöcker IM, Bahtz R, Komorowski L, Stöcker W, Kastrup A, Kuthe M, Meinch HM. Progressive encephalomyelitis with rigidity and myoclonus: A new variant with DPPX antibodies. Neurology 82(17): 1521-1528 (2014).
  3. Banczyk D, Kalies K, Nachbar L, Bergmann L, Schmidt P, Bode U, Teegen B, Steven P, Lange T, Textor J, Ludwig R, Stöcker W, König P, Bell E, Westermann J. Activated CD4(+) T cells enter the splenic T-cell zone and induce autoantibody-producing germinal centers through bystander activation. Eur J Immunol 44(1):93-102 (2014).
  4. Busse S, Busse M, Brix B, Probst C, Genz A, Bogerts B, Stöcker W, Steiner J. Seroprevalence of N-methyl-D-aspartate glutamate receptor (NMDA-R) autoantibodies in aging subjects without neuropsychiatric disorders and in dementia patients. Eur Arch Psychiatry Clin Neurosci, 264(6): 545-550 (2014).
  5. Busse S, Brix B, Kunschmann R, Bogerts B, Stoecker W, Busse M. N-methyl-D-aspartate glutamate receptor (NMDA-R) antibodies in mild cognitive impairment and dementias.Neurosci Res, 85: 58-64 (2014).
  6. Corman VM, Jores J, Meyer B, Younan M, Liljander A, Said MY, Gluecks I, Lattwein E, Bosch BJ, Drexler JF, Bornstein S, Drosten C, Müller MA. Antibodies against MERS coronavirus in dromedary camels, Kenya, 1992-2013. Emerg Infect Dis 20(8): 1319-1322 (2014).
  7. Dahm L, Ott C, Steiner J, Stepniak B, Teegen B, Saschenbrecker S, Hammer C, Borowski K, Begemann M, Lemke S, Rentzsch K, Probst C, Martens H, Wienands J, Spalletta G, Weissenborn K, Stöcker W, Ehrenreich H. Seroprevalence of autoantibodies against brain antigens in health and disease. Annals of Neurology, 76(1): 82-94 (2014).
  8. Dammermann W, Bochmann D, Bentzien F, Komorowski L, Steinhagen K, Ullrich S, Lunzen van J, Lüth S. CMV specific cytokine release assay in whole blood is optimized by combining synthetic CMV peptides and toll like receptor agonists. J Immunol Methods 414: 82-90 (2014).
  9. Doss S, Nümann A, Ziegler A, Siebert E, Borowski K, Stöcker W, Prüss H, Wildemann B, Endres M, Jarius S. Anti-Ca/anti-ARHGAP26 antibodies associated with cerebellar atrophy and cognitive decline. J Neuroimmunol 267(1-2): 102-104 (2014).
  10. Doss S, Wandinger KP, Hyman B, Panzer J, Synofzik M, Dickerson B, Mollenhauer B, Scherzer CR, Ivinson AJ, Finke C, Schöls L, Müller von Hagen J, Jahn H, Höltje M, Biswal BB, Harms L, Ruprecht K, Buchert R, Höglinger GU, Oertel WH, Unger MM, Priller J, Spruth EJ, Paul F, Meisel A, Lynch D, Dirnagl U, Endres M, Teegen B, Probst C, Komorowski L, Stöcker W, Dalmau J, Prüss H. High prevalence of NMDA receptor IgA/IgM antibodies in different types of dementia.  Ann Clin Trans Neurol 1(10): 822-832 (2014).
  11. Drosten C, Meyer B, Müller MA, Corman VM, Al-Masri M, Hossain R, Madani H, Sieberg A, Bosch JB, Lattwein E, Alhakeem RF, Assiri AM, Hajomar W, Albarrak AM, Al-Tawfiq JA, Zumla AI, Memish ZA. Transmission of MERS-coronavirus in household contacts. N Engl J Med 371(9): 828-835.
  12. Finke C, Mengel A, Prüss H, Stöcker W, Meisel A, Ruprecht K. Anti-NMDAR encephalitis mimicking HaNDL syndrome. Cephalalgia 34(12): 1012-1014 (2014).
  13. Hammer C, Stepniak B, Schneider A, Papiol S, Tantra M, Begemann M, Sirén A-L, Pardo LA, Sperling S, Mohd Jofrry S, Gurvich A, Jensen N, Ostmeier K, Lühder F, Probst C, Martens H, Gillis M, Saher G, Assogna F, Spalletta G, Stöcker W, Schulz TF, Nave K-A, Ehrenreich H. Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity. Mol Psychiatry 19(10):1143-1149 (2014).
  14. Jarius S, Kleffner I, Dörr JM, Sastre-Garriga J, Illes Z, Eggenberger E, Chalk C, Ringelstein M, Aktas O, Montalban X, Fechner K, Stöcker W, Ringelstein EB, Paul F, Wildemann B. Clinical, paraclinical and serological findings in Susac syndrome: an international multicenter study. J Neuroinflammation 11(1): 46 (2014).
  15. Jarius S, Friedemann P, Fechner K, Ruprecht K, Kleiter I, Franciotta D, Ringelstein M, Pache F, Aktas O, Wildemann B. Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate. J Neuroinflammation 11(1): 129 (2014).
  16. Jarius S, Scharf M, Begemann N, Stöcker W, Probst C, Serysheva I, Nagel S, Graus F, Psimaras D, Wildemann B, Komorowski L. Antibodies to the inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1) associated with cerebellar ataxia. J Neuroimmunol 11(1):206(2014).
  17. Langenhan J, Dworschak J, Saschenbrecker S,  Komorowski L, Schlumberger W, Stöcker W, Westermann J, Recke A, Zillikens D, Schmidt E, Probst C. Specific immunoadsorption of pathogenic autoantibodies in pemphigus requires the entire ectodomains of desmoglein. Exp Dermatol 23(4): 253-259 (2014).
  18. Malter MP, Frisch C, Schöne-Bake JC, Helmstädter C, Wandinger KP, Stöcker W, Urbach H, Elger CE, Vincent AV, Bien CG. Outcome of limbic encephalitis with VGKC-complex antibodies: relation to antigenic specificity. J Neurol 261(9): 1695-1705 (2014).
  19. Meyer B, Müller MA, Corman VM, Reusken CB, Ritz D, Godecke GJ, Lattwein E, Kallies S, Siemens A, van Beek J, Drexler JF, Muth D, Bosch BJ, Wernery U, Koopmans MP, Wernery R, Drosten C. Antibodies against MERS coronavirus in dromedaries, United Arab Emirates, 2003 and 2013. Emerg Infect Dis 20(4): 552-559 (2014).
  20. Müller MA, Corman VM, Jores J, Meyer B, Younan M, Liljander A, Bosch BJ, Lattwein E, Hilali M, Musa BE, Bornstein, S, Drosten C. MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983-1997. Emerg Infect Dis 20(12): 2093-2095 (2014).
  21. Müller UJ, Teegen B, Probst C, Bernstein HG, Busse S, Bogerts B, Schiltz K, Stoecker W, Steiner J. Absence of dopamine receptor serum autoantibodies in schizophrenia patients with an acute disease episode. Schizophr Res 158(1-3): 272-274 (2014).
  22. Nühs A, Schäfer C, Zander D, Trübe L, Tejera Nevado P, Schmidt S, Arevalo J, Adaui V, Maes L, Dujardin JC, Clos J. A novel marker, ARM58, confers antimony resistance to Leishmania spp. Int J Parasitol Drugs Drug Resist 4(1): 37-47 (2014).
  23. Probst C, Saschenbrecker S, Stöcker W, Komorowski L. Anti-neuronal autoantibodies: current diagnostic challenges. Multiple Sclerosis and Related Disorders 3(3): 303-320 (2014).
  24. Prüss H, Rothkirch M, Kopp U, Hamer HM, Hagge M, Sterzer P, Saschenbrecker S, Stöcker W, Harms L, Endres M. Limbic encephalitis with mGluR5 antibodies and immunotherapy-responsive prosopagnosia. Neurology, 83(15): 1384-1386 (2014).
  25. Prüss H, Hoffmann C, Saschenbrecker S, Ebinger M. A case of inflammatory peripheral nerve destruction antedating anti-NMDA receptor encephalitis. Neurol Neuroimmunol Neuroinflamm 1(2):e14 (2014).
  26. Prüßmann J, Prüßmann W, Recke A, Rentzsch K, Juhl D, Henschler R, Müller S, Lamprecht P, Schmidt E, Csernok E, Görg S, Stöcker W, Zillikens D, Ibrahim SM, Ludwig RJ. Co-occurrence of autoantibodies in healthy blood donors. Exp Dermatol, 23(7): 519-521 (2014).
  27. Schlumberger W, Hornig N, Lange S, Probst C, Komorowski L, Fechner K, Dähnrich C, Stöcker W. Differential diagnosis of membranous nephropathy with autoantibodies to phospholipase A2 receptor 1. Autoimmun Rev 13(2): 108-113 (2014).
  28. Steiner J, Teegen B, Schiltz K, Bernstein HG, Stoecker W, Bogerts B. Prevalence of N-methyl-d-aspartate receptor autoantibodies in the peripheral blood: healthy control samples revisited. JAMA Psychiatry, 71(7): 838-839 (2014).
  29. Timmermans SA, Damoiseaux JG, Heerings-Rewinkel PT, Ayalon R, Beck LH Jr, Schlumberger W, Salant DJ, Paassen van P, Tervaert JW. Evalutation of anti-PLA2R1 as measured by a novel ELISA in patients with idiopathic membranous nephropathy: a cohort study. Am J Clin Pathol 142(1): 29-34 (2014).
  30. Tobin WO, Lennon VA, Komorowski L, Probst C, Clardy SL, Aksamit AJ, Appendino JP, Lucchinetti CF, Matsumoto JY, Pittock SJ, Sandroni P, Tippmann-Peikert M, Wirrell EC, McKeon A. DPPX potassium channel antibody: Frequency, clinical accompaniments, and outcome in 20 patients. Neurology 83(20): 1797-1803 (2014).
  31. Waters P, Reindl M, Schanda K,  Tuller F, Kral V, Nytrova P, Sobek O, Nielsen HH, Illés Z, Barington T, Lillevang ST, Stöcker W, Rentzsch K, Probst C, Saschenbrecker S, Klingbeil C, Krummrei U, Berthele A, Berki T, Granieri L, Bertolotto A, Giometto B, Zuliani L, Hamann D, Saiz A, Höftberger R, Comabella M, Riu CC, Siva A, Altintas A, Deniz G, Vincent A, Leite MI, Woodhall M, Palace J, Paul F, Aktas O, Jarius S, Vedler C, Ruiz A, Marignier R. Assessment of aquaporin-4(AQP4) antibody assays in European diagnostic centres. J Neuroimmunol 275(1-2):15 (2014).
  32. Wolf J, Hasenclever D, Petroff D, Richter T, Uhlig HH, Laaß MW, Hauer A, Stern M, Bossuyt X, de Laffolie J, Flemming G, Villalta D, Schlumberger W, Mothes T. Antibodies in the diagnosis of coeliac disease: A biopsy-controlled, international, multicentre study of 376 children with coeliac disease and 695 controls. PLoS One 9(5): e97853 (2014).
  1. Axel K, Pfeiffer T, Koerner D, Zieseniss S, Steller U. Microarray based analysis of the genetic risk factors HLA-DQ2/DQ8 in the diagnosis of coeliac disease. 9. International Congress on Autoimmunity, Nizza, Frankreich (2014).
  2. Bahtz R, Blöcker IM, Begemann N, Denno Y, Tiede S, Teegen B, Stöcker W, Probst C, Komorowski L. Identification of septin complex as an autoantibody target in paraneoplastic cerebellar ataxia.12. International Congress of Neuroimmunology (ISNI), Mainz, Deutschland (2014).
  3. Bahtz R, Teegen B, Borowski K, Probst C, Blöcker IM, Fechner K, Parigger S, Daniel G, Brücke T, Lauenstein AS, Schrank B, Stöcker W, Komorowski L. Autoantibodies against IgLON5: two new cases. 12. International Congress of Neuroimmunology (ISNI), Mainz, Deutschland (2014).
  4. Biesen R, Rose T, Klotsche J, Enghard P, Dzionek A, Ozimkowski T, Schlumberger W, Burmester GR, Alexander T, Grützkau A, Hiepe F. A biomarker benchmark study for monitoring SLE activity: Only SIGLEC-1 and C3 are better than flipping a coin. 42. Jahrestagung der Deutschen Gesellschaft für Rheumatologie (DGRh), Düsseldorf, Deutschland (2014).
  5. Blöcker IM, Mindorf S, Stöcker W, Balint B, Meinck HM, Komorowski L, Probst C, Schlumberger W. A new recombinant cell-based IFA for the determination of autoantibodies to GAD in stiff-person syndrome. 12. International Congress of Neuroimmunology (ISNI), Mainz (2014).
  6. Brix B, Golz JM, Stöcker W, Schlumberger W, Busse S. Plaque specific autoantibodies in dementia. 9. International Congress on Autoimmunity, Nizza, Frankreich (2014).
  7. Brix B, Zeplin K, Klingbeil C, Stoops E, Vanderstichele H, Herbst V. CSF proficiency panel for the Alzheimer’s biomarker assays. Alzheimer‘s Association International Conference (AAIC), Kopenhagen, Dänemark (2014).
  8. Cavalar M, Harder M, Hellberg L, Opelka P, Götzl J, Steller U. A new microarray-based HPV test system for the simultaneous detection and typing of 30 relevant high- and low-risk anogenital HPV. International Papilloma Virus Conference, Seattle, USA (2014).
  9. Cavalar M, Harder M, Hellberg L, Opelka P, Götzl J, Steller U. A new microarray-based HPV test system for the simultaneous detection and typing of 30 relevant high- and low-risk anogenital HPV. Deutscher Kongress der Laboratoriumsmedizin (DGKL), Mannheim, Deutschland (2014).
  10. Demeyer L, Stoops E, Mauroo K, Struyfs H, Herbst V, Engelborghs S, Brix B, Vanderstichele H. Quantification of CSF Aβ1-38, together with apolipoproteins E, can improve the clinical diagnostic accuracy for Alzheimer’s disease of the CSF tau and Aβassays. Alzheimer‘s Association International Conference (AAIC), Kopenhagen, Dänemark (2014).
  11. Ewers N, Schuett S, Kuhlencord A, Warnecke JM, Steinhagen K, Schlumberger W. EUROIMMUN Dengue Virus NS1 ELISA is more sensitive than Panbio® DengueEarly ELISA for early detection of dengue virus infection. International Meeting on Emerging Diseases and Surveillance (IMED), Wien, Österreich (2014).
  12. Hansson-Hamlin H, Bremer H, Lilliehook I, Lattwein E, Rönnelid J. Antinuclear antibody specificity in dogs with immune-mediated rheumatic disease. 24. European Congress of Veterinary Internal Medicine (ECVIM), Mainz, Deutschland (2014).
  13. Herbst V, Zeplin K, Stoops E, Vanderstichele H, Brix B. Automation of amyloid ELISAs brings Alzheimer’s biomarker standardisation one step further. Alzheimer‘s Association International Conference (AAIC), Kopenhagen, Dänemark (2014).
  14. Komorowski L, Rentzsch K, Saschenbrecker S, Teegen B, Probst C, Stöcker W. Multiplex testing of anti-neuronal autoantibodies. American Academy of Neurology (AAN) 66. Annual Meeting, Philadelphia, USA (2014).
  15. Lattwein E, Lipkowski M, Rohwäder E, Fechner K. Effizientes Gesundheitsmonitoring von Labormäusen gemäß FELASA-Empfehlung mittels Immunfluoreszenztest-Mosaiken. 33. Jahrestagung des Arbeitskreises für Veterinärmedizinische Infektionsdiagnostik (AVID), Kloster Banz, Deutschland (2014).
  16. Liljander A, Corman VM, Meyer B, Younan M, Said MY, Gluecks I, Lattwein E, Bosch BJ, Drexler JF, Bornstein S, Müller MA, Jores J, Drosten C. Presence of Middle East Respiratory Syndrome (MERS) coronavirus antibodies in East African dromedary camels. Tropentag 2014 „Bridging the gap between increasing knowledge and decreasing resources“, Prag, Tschechien (2014).
  17. Probst C, Blöcker IM, Mindorf S, Unger M, Fechner K, Meinck HM, Balint B, Stöcker W, Schlumberger W, Komorowski L. Autoantibodies against glycine-associated synaptic proteins in stiff-person syndrome. 12. International Congress of Neuroimmunology (ISNI), Mainz, Deutschland (2014).
  18. Scharf M, Blöcker IM, Borowski K, Teegen B, Begemann N, Denno Y, Tiede S, Stöcker W, Probst C, Schlumberger W, Komorowski L. Identificaton of the inositol 1,4,5-triphosphate receptor type 1 as a new autoantigen of Purkinje cells. 12. International Congress of Neuroimmunology (ISNI), Mainz, Deutschland (2014).
  19. Stoops E, Demeyer L, Mauroo K, Herbst V, Brix B, Coart E, Vanderstichele H. Multi-center precision study for novel CE-labelled Aβ1-40, Aβ1-42 and total tau ELISAs reveals excellent precision in different labs. Alzheimer‘s Association International Conference (AAIC), Kopenhagen, Dänemark (2014).
  20. Sutphen C, Shah AR, Jasielec MS, Xiong C, Vlassenko AG, Benzinger T, Stoops E, Vanderstichele H, Brix B, Darby H, Vandijck M, Ladenson JH, Holtzman DM, Morris JC, Fagan AM. Longitudinal changes in cerebrospinal fluid biomarkers of Alzheimer’s disease: Findings from a cognitively normal, middle-aged cohort. Alzheimer‘s Association International Conference (AAIC), Kopenhagen, Dänemark (2014).
  21. Venkataraman I, Brix B, Stoecker W, Schlumberger W, Busse S. Antigenic targets of autoantibodies in dementia. Alzheimer‘s Association International Conference (AAIC), Kopenhagen, Dänemark (2014).
  22. Waters P, Reindl M, Schanda K, Kral V, Nytrova P, Sobek O, Hvilsted Nielsen H, Illés Z, Barington T, Lillevang ST, Stöcker W, Rentzsch K, Probst C, Saschenbrecker S, Klingbeil C, Krummrei U, Berthele A, Berki T, Granieri L, Bertolotto A, Giometto B, Zuliani L, Hamann D, Saiz A, Höftberger R, Comabella M, Costa Riu C, Siva A, Altintas A, Deniz G, Vincent A, Leite MI, Woodhall M, Palace J, Friedemann P, Aktas O, Jarius S, Vedeler C, Ruiz A, Marignier R. Assessment of aquaporin-4 (AQP4) antibody assays in European diagnostic centres. 12. International Society of Neuroimmunology (ISNI) Congress, Mainz, Deutschland (2014).
  23. Westermann J, Denczyk E, Probst C, Komorowski L, Schlumberger W. Non-radioactive detection of autoantibodies against acetylcholine receptors by presenting the complete epitope spectrum. 9. International Congress on Autoimmunity, Nizza, Frankreich (2014).
  1. Fechner K. 1. Interpretation von Ringversuchen: Wie gehe ich mit „falschen“ Ergebnissen um? 2. EUROPattern: Automatische Auswertung von IFT-Mustern für ANA, ANCA und dsDNS. EUROIMMUN-Seminar (Fortbildung) „Indirekte Immunfluoreszenz“, Wien, Österreich (2014).
  2. Fechner, K. Computer-aided immunofluorescence microscopy (CAIFM) for ANA diagnostics. 9. International Congress on Autoimmunity, Nizza, Frankreich (2014).
  3. Lattwein E, Renneker S, Steinhagen K, Müller HA, Memish ZA, Drosten C. Von Kamelen und Menschen – Untersuchung mit den ersten kommerziellen ELISA und Immunfluoreszenztests zum Nachweis von Antikörpern gegen MERS-Coronaviren. 33. Jahrestagung des Arbeitskreises für Veterinärmedizinische Infektionsdiagnostik (AVID), Kloster Banz, Deutschland (2014).
  4. Lattwein E. Investigations using the first commercial ELISA and IFT for the detection of antibodies against MERS coronavirus of camels and men. 5. International Conference of Egyptian society of virology, Hurghada, Ägypten (2014).
  5. Probst C. RC IFA: The fastest way for the translation of novel antibody markers to the diagnostic lab. 3. Translational Immunology School, Potsdam, Deutschland (2014).
  6. Probst C. GABA receptor antibodies in neurological diseases and their detection by recombinant cell based Immunfluorescence assay – the fastest way for the translation of novel antibody markers to the diagnostic lab. 2. International Meeting on Nerve-driven Immunity: Neurotransmitter and Neuropeptides in the Immune System, Stockholm, Schweden (2014).
  7. Schlumberger W. 1. Autoantibody diagnostics in autoimmune nephropathies. 2. The diagnostic puzzle in celiac disease. Arab Health Congress/ Medlab, Dubai, Vereinigte Arabische Emirate (2014).
  8. Schlumberger W. Autoantibodies in Renal Autoimmune Diseases. 12. International Workshop on Autoimmunity and Autoantibodies, São Paulo, Brasilien (2014).
  9. Schlumberger W. Autoantikörper-Diagnostik bei autoimmunen Nephropathien. Medica Education Conference, Düsseldorf, Deutschland (2014).
  10. Stöcker W. Latest achievements towards a complete automization of indirect immunofluorescence. 3. National Autoimmune Diagnostics Summit, Guangzhou, China (2014).
  11. Stöcker W. Diagnostik von Autoantikörpern bei Patienten mit neurologischen Erkrankungen. Fortbildungsveranstaltung: 60 Jahre neurologische Klinik Görlitz. Görlitz, Deutschland (2014).
  1. Herbst V, Nagel B. Vorrichtung und Verfahren zur Aufbewahrung und zum Transport einer Körperflüssigkeitsprobe. German and international patent application DE 10 2013 211 918.6 (filed 2013) and WO 2014/206531 (filed 2014).
  2. Meyer W, Scheper T. Kalibrationsstreifen für einen Immunoblot. Chinese and European patent application CN 103 827 670 (filed 2012) und EP 2 758 783 (filed 2012).
  3. Meyer W, Scheper T, Kaffka R. Verfahren zur automatisierten Auswertung von inkubierten Blotstreifen. German and international patent application. DE 10 2013 008 468.7 (filed 2013) and WO 2014/173657 (filed 2014).
  4. Scheper T., Meyer W., Langner J. Verfahren und Vorrichtung zur Diagnose eines Nasopharynx-Karzinoms. German and international patent application DE 10 2013 001 699.1 (filed 2013) and WO 2014/118151 (filed 2014).
  5. Stöcker W, Rottmann N. Verfahren und Analysevorrichtung zur mikroskopischen Untersuchung eines Gewebeschnittes oder eines Zellausstriches. German and international patent application DE 10 2012 013 678 (filed 2012) and WO2014/009066 (filed 2013).
  6. Stöcker W, Rottmann N. Verfahren sowie Vorrichtung zur Inkubation von Patentientenproben. German and international patent application DE 10 2012 013 680 (filed 2012) and WO 2014/009067 (filed 2013).
  7. Stöcker W, Meyer W, Scheper T, Euken A. Testkit für die Labordiagnostik. US patent application US 2014/0186971 (filed 2013).
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